Different domain name in Send From: and Replay To: fields = SPAM?

Hello,
Is there any increase in chances that the messages that have different domain name in Send From: and Reply To: fields will be filtered as spam and thus reduce deliverability? Spammers are often using different domains for Send & Reply to protect their identity.

Hi @mr108 , that’s a good question.

That’s possible, but I’m sure it’s not the only indicator; probably it is one of the many elements taken into account to decide whether or not an email should be considered spam or not.
I’m not THE expert of this field though.